Folic Acid

Appearance

Yellowish or orange crystalline powder

Yellowish crystalline powder

Specific Rotation

+18 ~ +22^o

19.2^o

Ultraviolet Absorption

A256/A365=2.80 ~ 3.0

2.92

Chromatograms (HPLC)

Conforms

Conforms

Identification (TLC)

Conforms

Conforms

Related Substance

Impurity A: <0.5%
Impurity D: <0.6%
Other impurity: <0.5%
Total impurity: <1.0%

0.4
0.5
0.4
0.7

Free Amines

<1/6

<1/6

Chromatographic purity

<2.0%

1.72%

Loss on drying

5.0% ~ 8.5%

7.7%

Residue on ignition

<0.2%

0.13%

Organic volatile impurities

Meet the requirements

Meet the requirements

Assay (on dried basis)

96.0 ~ 102.0%

97.30%

Conclusion: This batch complies with BP2005/ USP30 and in-house specifications

Storage: Preserve in well-closed, light-resistant containers

Shelf life: 48 months